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Wednesday, 20 January 2010 09:53

AstraZeneca

Written by ODISHAMEDICAL.COM
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AstraZeneca plc (LSE: AZN, NYSE: AZN, OMX: AZN) is a British-Swedish pharmaceutical company formed on 6 April 1999 by the remerger of Swedish Astra AB and British Zeneca Group plc. Zeneca had been part of Imperial Chemical Industries (ICI), as three divisions that were spun off from ICI on 1 June 1993. It is a public company and is listed on the London Stock Exchange, the New York Stock Exchange and the OMX exchange. It is a constituent of the FTSE 100 Index.

 

History

The company's origins date from 1912, when Atlas Chemical Industries was founded by demerger from DuPont in Wilmington, Delaware, United States, in 1912. Subsequently, Atlas Chemical Industries acquired Stuart Pharmaceuticals (founded by Arthur Hanisch in Pasadena, California, U.S., in 1941) in 1961 before itself being bought by ICI in 1972. In 1993 ICI demerged this pharmaceuticals business, as well as its agrochemicals and specialties businesses, to form Zeneca Group plc.

Astra AB was founded in 1913 by 400 doctors and apothecaries in Södertälje, Sweden. In 1949 the company developed Xylocaine, a local anesthetic.[clarification needed] In 1994 the company formed a joint venture with Merck to market Losec, an ulcer-treatment drug.

In 1999 Astra AB and Zeneca Group plc merged to form AstraZeneca plc.

In 2005 the company announced an arrangement with Astex for the discovery, development and commercialisation of novel small molecule inhibitors of protein kinase B for use as anti-cancer agents. In the same year it announced a collaboration with Avanir for research and licensing in the area of Reverse Cholesterol Transport (RCT) enhancing compounds for the treatment of cardiovascular disease. It also announced an alliance with Schering AG for research and licensing in the area of selective glucocorticoid receptor agonists (SEGRAs). It also announced that it had become a Diamond Member of the Pennsylvania Bio commerce organization.

In 2006, following a collaborative relationship begun in 2004, AstraZeneca acquired Cambridge Antibody Technology in a deal worth £702 million[clarification needed].

Also in 2006 it formed an alliance with Abbott Laboratories in relation to Crestor and TriCor, commencing that year and extending to at least 2009.

In 2007 it reported that it had entered into an alliance with Bristol-Myers Squibb to form a global collaboration to develop and commercialise two investigational drugs (saxagliptin and dapagliflozin) beginning from 2007.

Also in 2007 AstraZeneca acquired MedImmune for about $15.2 billion. AstraZeneca consolidated its biologics portfolio in MedImmune and Cambridge Antibody Technology which was rebranded to create a dedicated biologics division known as 'MedImmune'

Operations

AstraZeneca develops, manufactures, and sells pharmaceuticals to treat disorders in the gastrointestinal, cardiac and vascular, neurological and psychiatric, infection, respiratory, pathological inflammation and oncology areas.

The corporate headquarters are in London, United Kingdom, the research and development (R&D) headquarters are in Södertälje. Major R&D centres are located in India, Sweden, the U.K. and the U.S. AstraZeneca has a large R&D centre in Cheshire, U.K.; this centre acts as one of Zeneca's main hubs.

AstraZeneca has laboratories in a large country estate on the east side of the A34 road north of the Monk's Heath crossroads in Cheshire in England.

 

Last modified on Wednesday, 20 January 2010 11:04
ODISHAMEDICAL.COM

ODISHAMEDICAL.COM

What is Telemedicine?

Here is the definition I have used over the past ten years or so to describe Telemedicine:"Telemedicine is the ability to provide interactive healthcare utilizing modern technology and telecommunications."

Basically, Telemedicine allows patients to visit with physicians live over video for immediate care or capture video/still images and patient data are stored and sent to physicians for diagnosis and follow-up treatment at a later time. Whether you live in the center of a Metro City or deep in the Remote Village, Telemedicine is an invaluable tool in Healthcare.

Here's an example of how Telemedicine works everyday. Say you have a horrible sore throat and visit your healthcare provider (could be a general practice physician, nurse practitioner, or unlicensed health worker in a village depending where you live), who does an examination and is concerned with what he sees. Your provider recommends a referral to an ENT specialist for a follow up diagnosis and treatment plan. Well, instead of traveling to the nearest specialist, which depending where you live could be anywhere from a 45-minute drive or an 18-hour ride, your provider connects you directly to the ENT specialist via Telemedicine.

Here are some of the major benefits of a Telemedicine Consultation:

The specialist actually hears your medical history and current condition directly from you and your provider instead of the specialist receiving a dictated note in the mail.

With the use of ENT medical peripherals such as a nasopharyngoscope, your provider can pass this medical peripheral into your nasal passage which will allow your provider and the ENT specialist simultaneous crystal clear video of your throat and vocal cords. The specialist may ask you to cough, pronounce letters, etc. in order to get the best outcome for the diagnosis.

The specialist can diagnose and recommend treatment immediately.

Your provider has the opportunity throughout the examination to ask questions and learn from each and every consultation. The continual education of your provider via medical consultations is an immeasurable benefit to all his patients.

Telemedicine Usage Models

Real-Time

This is the most common use in Telemedicine. Like the example above, live video allows the provider, patient and specialist to all communicate together to achieve the best outcome for the patient.

In or outpatient specialty consultation

Physician supervision of non-MD clinician

Generally require higher bandwidths (minimum 256kb)

Store and Forward (asynchronous)

Used when both health providers are not available or not required at the same time. The provider's voice or text dictation on the patient's history, current affliction including pictures and/or video, radiology images, etc., are attached for diagnosis. This record is either emailed or placed on a server for the specialist's access. The specialist then follows up with his diagnosis and treatment plan.

Teleradiology

Can be done over low or high bandwidth

Images scanned, direct capture, or digital camera

Other specialties consist of dermatology, ophthalmology, pathology

Home Health Telemedicine

When a patient is in the hospital and he is placed under general observation after a surgery or other medical procedure, the hospital is usually losing a valuable bed and the patient would rather not be there as well. Home health allows the remote observation and care of a patient. Home health equipment consists of vital signs capture, video conferencing capabilities, and patient stats can be reviewed and alarms can be set from the hospital nurse's station, depending on the specific home health device.

Usually low bandwidth analog Plain Old Telephone System (POTS). Some newer systems do support higher bandwidth capabilities.

Disease management, post-hospital care, assisted living, etc.

Summary of Benefits of Telemedicine:

To Rural Physicians and clinics (spoke sites) Receive education from the specialist/provider

Better health outcome for their patients

Enhanced community confidence in local healthcare

Attend continuing medical education courses from their clinic

To Patients

Loved ones remain in their community with family support

Cost savings from not having to travel extensively

Immediate urgent care

Confidentiality of specialty examination or visit (Because the patient visits the general practice doctor, he can be seen for any specialty care without anyone else knowing)

Patient education courses (nutrition, oncology, etc.)

Properly stabilize patient prior to transport

Early Diagnosis prior to escalated medical episode

Rural Patient's Community

Dollars follow the patient

Patients that routinely travel to visit doctors in large urban areas tend to purchase their goods and services from those cities, Telemedicine keeps those dollars local.

To Telemedicine Providers (hub sites)

Expand patient outreach

Major surgical procedures resulting from the initial telemedicine consultation

Reduction in ER visits

Promotion of Hospital

Charge tuition for clinician education courses (CME, CNE, etc.)

How can we give any hospital or clinic immediate access to a vast amount of medical experts, healthcare education/information, and support from other physicians.

How can we take all these resources and share them immediately and effectively with any hospital or clinic in the world?

We can use Telemedicine!

 

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1 comment

  • Comment Link dillip moharana Monday, 01 February 2010 12:08 posted by dillip moharana

    It'S VERY NICE TO HAVE ASTRA ZENECA among top 10 com. of world,being the employee I feel proud of it.

    This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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